Deep Prime on tiff files(scans of dia positives)?

This is practically useless, as DP or DP-XD will get rid of the noise that is generated by the camera. The noise in scans, however, is mainly the grain in the film. Applications like NeatImage are the way to go, as they analyze the noise in the scan, build a noise profile and remove the noise with limited impact on the scan quality. See e.g. my example in DXO PL Deep prime and Vuescan - #35 by HanSch

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