When I set my MBA screen to 1280 x 800, GUI elements start to overlap.
The blue tab overlaps the Compare button…
The Reset button overlaps its LH neighbour…
DPL6 is perfectly capable to run with this screen size settings, but some of the GUI elements need to be less wide to make it work nicely.
DPL5 is better, but needs some adjustment at the RH part of the toolbar.
(Tested with DPL 5.5.81 and 6.0.1.25 on macOS Ventura 22A380 on M1 MBA 2020)