Not in my case.
Which camera/lens do you have in mind?
I did some experiments with a photo made by D90/18-200DX (12mpx, APS-C, superzoom) at 18mm, f/4.5, ISO 400, close focus. No problems with that – some heavy green/magenta CA spanning 3-5 pixels at the corners was removed quite effectively by PL8.5/Win. Interestingly, even when CA corrections are disabled, DeepPRIME3 alone does remove most of CA, even for low noise photo, with no such effect when using XD2s (or no NR) (EDIT: it’s more complicated, see my next reply). This can be seen using Loupe or in exported jpegs. If you use very high settings for ClearVision or Saturation (e.g. low-contrast photos, scattered light with desaturated colors, like haze, dust, or deep underwater), having only CA in mind, it seems better to use DP3 than XD2s or No NR. Might be case dependent, though.
Since my PL7 trial, my presets have ‘Lateral CA’ checkbox marked, ‘Purple fringing’ cleared, ‘Intensity’ and ‘Size’ set to Auto. Never had to look back and no problems seen with PL8.5 so far. However, for things like Plena/Z8 there’s no visible CA, so PL CA corrections are not effective indeed 