OS X Photos is somehow closed to external programs, and you can only edit Photos using the available extensions.
What you need to consider, and which is important in your workflow, is that if you use only one extension to edit your RAW, you still benefit on RAW format.
BUT, as long as you use several plugins, you won't be able to use RAW format anymore, as the exchange format between different extensions, and OS X Photos itself, will be processed JPG.
So we suggest to first edit your RAW format with OpticsPro for Photos, then once done, you will be able to edit processed JPG with other extensions and OS X Photos ... otherwise, you will be only able to edit processed JPD with OpticsPro for Photos.
Hope that is clear for you, if not, let me know.